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KMID : 0361020010440050499
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Korean Journal of Otolaryngology - Head and Neck Surgery
2001 Volume.44 No. 5 p.499 ~ p.505
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Result of Allergic Skin Test, MAST and Nasal Provocation Test in Children with Atopic Dermatitis
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신승엽/Seung Youp Shin
조중생/진영완/박상훈/문지호/차창일/Joong Saeng Cho/Young Wan Jin/Sang Hoon Park/Ji Ho Moon/Chang Il Cha
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Abstract
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Background & Objectives : Allergic diseases are considered to be systemic diseases. Atopic diseases are the first manifestation among allergic diseases, with the suggested relation to allergic rhinitis and asthma, as reported in several studies.
The
objective of this study was to evaluate the responses to allergic tests in children who have atopic dermatitis or have allergic rhinitis and atopic dermatitis. Materials & Methods : Eighty subjects without atopic dermatitis (control group) and 80
patients with atopic dermatitis (atopy group) were subjected to study from Nov. 1997 to Nov. 1999. The atopic group included pediatric patients who were diagnosed as having atopic dermatitis, but excluded patients who received medical treatment
of
steroid or antihistamine before the test for 1 month. In all the control and atopic groups, the nasal cavity volume was first estimated by acoustic rhinometry, followed by the allergic skin test (AST) and MAST. A nasal provocation test was taken
with a
positive allergen for patients who showed positive response to AST and MAST; for patients who showed negative response to AST and MAST, the test was taken with the House dust mites. Results : In the atopic dermatitis group, the rate of positive
responses to AST and MAST were 65% and 72.5%, respectively; in the control group, the rates were 25% and 35%, respectively. The most common positive allergen was the House dust mite in AST and MAST. In the nasal provocation test, the more
positive
rate
was observed in the atopic group. Conclusion : The atopic group showed more positive response than the control group to AST, MAST and the nasal provocation test. Also, the nasal mucosa of 37.5% of the atopic dermatitis patients were sensitized
to
a
certain allergen.
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KEYWORD
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